Development of Biphasic Calcium Phosphate Block

1.

Title of Product/Design/Equipment.

Development of Biphasic Calcium Phosphate Block

2.

IPR Status

Patent/Abroad IPR Details

Patent Application 2009DEL2013

3.

Application/Uses

Bone healing & synthetic bone graft.

4.

Salient Technical Feature including Competing Feature

The product novel three dimensional load bearing biphasic calcium phosphate nanocomposite is osteoinductive. It can induce the stem cells to differentiate into new bone forming cells. So the nanocomposite can be used as bone healing & synthetic bone graft. The mechanical compressive strength of the 3D BCP is in the range of 6-26 MPa analogous to cancellous bone.

5.

Level/Scale of Development

Process demonstrated at 100 gm/batch scale

6.

Environmental Consideration

No

7.

Status of Commercialization

The know-how transferred to G. Surgiwear Ltd, Shajahanpur

8.

Major Raw Material to be Utilized

Calcium salt and phosphate salts ammonium solution NH3, Distilled water, polymer

9.

Major Raw Plant Equipment and Machinery Required

Magnetic stirrer (rpm): 1000/min, pH meter, Mould made of perplex sheet (15 cm x 15 cm x 10 cm) & Distilled water plant Muffle Furnace

10.

Techno-Economics

For 100 gm/batch scale Capital Cost ~Rs. 5.0 Lakhs (excluding land & shed)

11.

Technology Package

(a) Process-Know-how, (b) Details of equipment, (c) Plant Layout & (d) Quality Assurance Methods. Assistance in setting up the plant on separate terms.